Many older people take a low dose of aspirin every day as a prescribed medication. Meanwhile, researchers found that the daily intake of aspirin can increase the risk of cancer or make it worse in older people.
The research was published recently in the Journal of the National Cancer Institute.
Recently, many health professionals have started prescribing aspirin to individuals who are at high risk of heart disease. Several experts also hope that this medication can lower the risk of old age diseases like dementia and even cancer.
Many studies suggest that a daily dose of aspirin can lower the risk of cancer among middle-aged people. This drug is particularly helpful in lowering the risk of colorectal cancer.
According to a previous study from March 2020, a daily aspirin dose had no positive effect on the health of older adults. This medication did not lower the risk of developing dementia and cognitive decline.
A recent study conducted among the people of the same age group shows that a low dose of aspirin every day can increase the risk of a cancer diagnosis. It also increases the risk of metastasized cancer of cancer which has spread in the body.
The findings of this study showed that there is a link between daily intake of aspirin and a higher rate of mortality due to cancer.
The study was conducted by scientists from Massachusetts General Hospital, Boston, and Monash University, Melbourne. The researchers analyzed the results from the trial of Aspirin in Reducing Events in the Elderly (ASPREE).
The ASPREE trial included 19,114 participants. These individuals were from the US and Australia. When the study started, no participant had heart disease, a physical disability, or dementia.
Most individuals in the study were older than 70 years. However, Hispanic and African American individuals from the US were around 65 years old.
The scientists suggested some people take a low dose of aspirin (100 mg) every day and others to take a placebo. After 4.7 years of follow up, researchers found that the people who took aspirin died due to several reasons. However, most of them died of cancer.
The recent study analyzed the effect of aspirin on an increased risk of cancer and cancer mortality. The difference in the incidence of cancer among the two groups who took aspirin and placebo was not very significant. However, the scientists found that the daily intake of aspirin led to a 19 percent increased risk of developing metastatic cancer. Also, those individuals had a 22 percent increased risk of an advanced cancer diagnosis.
This increased risk is in comparison to those individuals who took a placebo during that time. The data also showed that this group had a higher risk of advanced cancer mortality.
Aspirin is known to reduce inflammation in the body. According to the researchers, aspirin suppresses the immune response that limits the growth of cancer in the body. This causes cancer to spread and reach later stages.
The researchers also said that cancer in younger people and older adults behaves differently. Hence, the effect of aspirin is different in both age groups.